Hi Gary, like yourself I've owned various cars ranging from Mondeos to all of the german 3.
I bought a is300h 3 months ago. Going from previously owning a BMW 320d, I took the leap to lexus and its the best move I've ever made.
Mine to is a 2015 model with 50k on the clock. I opted for the Executive edition in Pearl White. Its a great spec example and has pretty much everything you'd need. I stayed away from the F Sport as the ride quality tends to ruin the experience for me anyway being too harsh.
My nearest dealer is 40 miles away which is no problem as its just another excuse to enjoy another ride out. Lol. Brilliant car you won't regret it if you want a top luxury quiet relaxing drive. Stick it in sport mode and its a completely different beast, will give you a lot quicker throttle response and probably leave a smile on your face!