I bought mine 3 months ago from a used car dealer near Manchester who gets a few in direct from Lexus Bolton, I think. Its a 2007 model which has the newer Nav and dvd player. Its an SR model and was looking for a SE-L, but the newer SE-L they had was tatty and had more miles on it. Mine had 84k with a full Lexus history which will now end as I use a local garage for servicing.
Since purchase I have put two new rear tyres on, replaced the navigation display (centre of the touch screen was unresponsive, so check before buying, I didn't!), got a new nav disc, purchased a luggage cover (these tend to disappear from used vehicles and are expensive second hand) and today have replaced the reversing camera which was working but the image on the screen wasn't the best.
Fortunately, mine has had the 10 year service just 1500 miles before I bought it, and water pump, cambelt etc was done already. You can also check on my lexus what has been done to the car since new at the dealership. Found that mine had a replacement gearbox at 39k.
Next purchase will be a Grom Vline to upgrade the ML entertainment.
Its a fantastic car to drive, quiet, smooth and economy during normal use, commute etc hovers around the 30 mark.