Carl, sorry to be slow in replying. My old car was top spec (except for the radar adjusted cruise control) and I miss some of the features. Yes, perhaps I ought to have hung out for a premier model on 17 inch wheels. Next time perhaps. I miss the top spec seats and proper leather interior, but not that much, now that i have (at last) adjusted the driver's seat just as I want it. I don't really miss the ML stereo. Now I am very serious about hi fi, but didn't regard the ML as proper hi fi. The DAB/FM radio/DVD in my car (Luxury with premium nav) is I think the one between the basic version and the ML version. The radio seems as good (and more versatile); the DVD isn't quite as good but I have bluetooth and USB audio so I can use my Apple devices. The car is essentially quieter at speed so the music eventually sounds just as good overall. Also, the premium nav is essential if you want the excellent reversing camera.
The new car has bi-xenon headlights, which is a big plus if (like me) you do a lot of night driving on unlit roads. I had xenons on the old SE-L, but is yours an SE-L or SE-l? If the former then you have them too, but otherwise this will be a useful improvement. One difference with my old car is that the old xenons were adaptive and coupled with a halogen pair for full beam. The adaptive bit made no practical difference that I could see. The new one has bi-xenons which I think are not quite as powerful on full beam as the old xenon-halogon combo, but better on dipped (better lens/projector?) which is where it really matters.
The nav system is more advanced, but more fiddly, as many have said before. No spare wheel, which is a minus. I might try to get hold of an old same saver, but in the event of a puncture I would need to find space somewhere for the old full size wheel, so that limits its value when fully laden.