Below is copied from a previous post, I could not get the links working.
For anyone considering getting a high mileage IS300h I would definitely say go for it as long as you've got full service history. I have privately owned my IS300h Premier from new since August 2013 and it is the best car I've ever had by miles. I have full Lexus main dealer servicing and have looked after it. I have now done 209k and it drives like new still getting over 50 mpg on my journey from Leicester to Birmingham every day for work. Had a new hybrid battery at 204k which was done under Lexus warranty, and I have full confidence this car will go for another 200,000+ miles.
Sadly I will be selling mine early next year as I have ordered a new NX 350h Takumi, although it did take me about 6 months to decide whether to to keep my IS for another few years or to order a new NX. I decided to go for the new NX as my wife and I why are approaching retirement and the IS is an extremely low car to get in and out of and we both now struggle, other than that I would have probably kept it longer.
Below is my link when I clocked 200k.
https://www.lexusownersclub.co.uk/forum/topic/133270-200000-miles-and-counting/
https://www.lexusownersclub.co.uk/forum/topic/135683-high-mileage-is-300h/?do=findComment&comment=1259534