IS250 2011 onwards have the following recommendations:
Oil grade:
0W-20, 5W-20, 5W-30 and 10W-30:
API grade SL “Energy-Conserving”, SM “Energy-Conserving”, SN “Resource-Conserving” or ILSAC multigrade engine oil
15W-40 and 20W-50:
API grade SL, SM or SN multigrade engine oil
SAE 0W-20 is filled into your Lexus vehicle at manufacturing, and the best choice for good fuel economy and good starting in cold weather.
If SAE 0W-20 oil is not avail- able, SAE 5W-30 oil may be used. However, it should be replaced with SAE 0W-20 at the next oil change.
If you use SAE 10W-30 or a higher viscosity engine oil in extremely low temperatures, the engine may become difficult to start, so SAE 5W-30 or lower viscosity engine oil is recommended.
Oil viscosity (0W-20 is explained here as an example):
The 0W in 0W-20 indicates the characteristic of the oil which allows cold startability. Oils with a lower value before the W allow for easier starting of the engine in cold weather.
The 20 in 0W-20 indicates the viscosity characteristic of the oil when the oil is at high temperature. An oil with a higher viscosity (one with a higher value) may be better suited if the vehicle is oper- ated at high speeds, or under extreme load conditions.