knowing you're a realist and aware of cars preponderances to wear-out .......... as said, depends on your proposed future use ....... also depends on your need for preventative and on-going maintenance ........... there's a reason why Lexus don't continue to warrant their cars in excess of 10 years young ....... bushes, suspension, and above all ELECTRONICS all have a tendency to maybe not have a particularly good extended life and which, when failing, will bring heartache and wondrous huge bills
I'm sure Drivetrain and bodywork and zero'ish rust issues BUT it's those niggling other mechanical thingys that tend to go awry in all cars, not just Lexus
Good luck with whatever you decide ..... my personal experiences with my Lexii have been just superb over the years, decades, and '00s of 000s of miles too
Malc