Due to a longstanding disability which has just gotten worse over time, I got a wheelchair today.
It's a folding self-propelled one, and I was afraid it wouldn't fit into the boot of my LS460. So with my girlfriend's help, we folded it up, and... it didn't fit :(
The rear air-con bulge was just too much in the way... I was getting disheartened and considering swapping my LS460 for an RX450 or similar just to get the chair in, and thinking of how much I would miss it.
Then found that my chair had quick release big wheels too. With them removed, the chair fits! The wheels also fit in the boot once separated
So the LS460 SE-L does take a folding wheelchair, certainly if it's this one...
http://www.amazon.co.uk/gp/product/B003G9LR8G/ref=oh_details_o02_s00_i00?ie=UTF8&psc=1